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Name: Xiaonong ZHANG
Title: Associate Professor
Office: Room 421, Material Building D
Platform: Institute of Composite Materials
Biodegradable metals and devices
The biodegradable alloys, containing nutrient elements (Mg, Zn, Ca, Fe, etc.), have excellent biocompatibility and biosafety. The developed biodegradable Mg-Zn alloy rods...
Biographical Information1987.9-1991.6, Department of Mechanical Engineering, Xi’an Jiao Tong University, B.S.
1991.9-1997.4, Department of Materials Science, Shanghai Jiao Tong University, M.S. and Ph.D.
1997.5-200.10, School of Materials Science and Engineering, Assistant, Lecturer and Associate Professor.
2000.11-2001.12, Department of Materials, Queen Marry University of London, Postdoctoral Research Fellow.
2002.1-now, School of Materials Science and Engineering, Associate Professor.
Research InterestsBiodegradable metals and devices
The biodegradable alloys, containing nutrient elements (Mg, Zn, Ca, Fe, etc.), have excellent biocompatibility and biosafety. The developed biodegradable Mg-Zn alloy rods with high strength are used in the manufacture of bone plates and screws, which not only possess good fixture effect, but also promote bone repair and accelerate bone healing. With the progressive degradation of the devices, they don’t need the second operation to be taken off. The high strength and toughness Mg-Zn alloy’s tubes and wires being used to staple, cardiovascular stent and so on, can reduce the restenosis rate and relieve the patients. Explores on the related animal experiments and clinical studies are of great significance in promoting the development and application of the bioabsorbable metallic materials.
Metal Matrix Composites
Selected Publications1. Xiaonong Zhang、Kang Sun，"Biological engineering principles and technology "Chapter 11," biomaterials technology ", Science Press, Beijing, published in September 2006
2. Renjie Wu、Xiaonong Zhang etc. co-translation, Materials Science and Technology Series 13 "The structure and properties of the composites", Science Press, Beijing, published in October 1999.
3. Jianan Li, Yang Song, Shaoxiang Zhang, Changli Zhao, Fan Zhang, Xiaonong Zhang, Lei Cao, Qiming Fan, Tingting Tang. In vitro responses of human bone marrow stromal cells to a fluoridated hydroxyapatite coated biodegradable Mg-Zn alloy, Biomaterials, 2010, 31 (22):5782-5788.
4. Yang Song, Shaoxiang Zhang, Jianan Li, Changli Zhao, Xiaonong Zhang. Electrodeposition of Ca-P coatings on biodegradable Mg alloy and in vitro biomineralization behaviors, Acta Biomaterialia, 2010, 6:1736-1742.
5. Shaoxiang Zhang, Xiaonong Zhang, Changli Zhao, Jianan Li, Yang Song, Chaoyin Xie, Hairong Tao, Yan Zhang, Yaohua He, Yao Jiang, Yujun Bian. Research of an Mg-Zn alloy as a degradable biomaterial. Acta Biomaterialia; 2010;6:626-640.
6. He Yaohua, Tao Hairong, Zhang Yan, Jiang Yao, Zhang Shaoxiang, Zhao Changli, Li Jianan, Zhang Beilei, Song Yang, Zhang Xiaonong. Biocompatibility of bio-Mg-Zn alloy within bone with heart, liver, kidney and spleen. Chinese Science Bulletin; 2009. 54(3): 484-491.
7. Changli Zhao, Peng Cao, Weiping Ji, Pei Han, Jihong Zhang, Fan Zhang, Yao Jiang, Xiaonong Zhang. Hierarchical titanium surface textures affect osteoblastic functionsJ Biomed Mater Res Part A 2011:99A:666–675.
8. Changli Zhao, Weiping Ji, Pei Han, Jihong Zhang, Yao Jiang, Xiaonong Zhang. In vitro and in vivo mineralization and osseointegration of nanostructured Ti6Al4V. J Nanopart Res (2011) 13:645–654.
9. Xiaonong Zhang, Weijie Lü, Di Zhang, Renjie Wu, Yujun Bian and Pingwei Fang. In Situ Technique for Synthesizing (TiB+TiC)/Ti Composites. Scripta Materialia, 1999, 41(1): 39-46.
10. Zhang Xiaonong, Zhang Di, Wu Renjie, Zhu Zhengang and Wang Can. Mechanical Properties and Damping Capacity of (SiCw + B4Cp)/ZK60A Mg Alloy Matrix Composite. Scripta Materialia, 1997, 37(11): 1631-1635.
Research ProjectsDr. Zhang has presided over and participated in more than 30 research projects including the national "863" High-Tech Program, the National Natural Science Foundation of China, Shanghai Nano Special Fund, and published more than 130 articles and edited two books, 12 invention patents, and won the Shanghai scientific and technological progress first and second prize each time.
2012 National Natural Science Foundation of China: Study on biodegradable behaviors and control mechanism of biomedical magnesium alloys and their devices under the action of stress.
Honors & Awards
Shanghai scientific and technological progress first and second prize.